By Alex Robles and Xochipilli
When THC is ingested, it is first absorbed into the bloodstream through the walls of the stomach and small intestine. From there, it is transported to the liver, where it is metabolized by enzymes into a chemical called 11-hydroxy-THC. This chemical is more potent than THC and can produce stronger effects, including an increased sense of euphoria and altered perceptions.
Once 11-hydroxy-THC is produced in the liver, it is transported back to the brain and other organs throughout the body. This process can take longer than the effects of smoked THC, often taking up to an hour or more to peak. The high from ingested THC may also last longer than the high from smoked THC.
When THC is smoked, it enters the bloodstream through the lungs and quickly reaches the brain, producing a more immediate and intense high. The effects of smoked THC can be felt within minutes and typically peak within half an hour.
The effects of THC can vary depending on the amount that is consumed and the individual’s metabolism and tolerance. In general, however, smoked THC can produce a more immediate and intense high, while ingested THC can produce a longer-lasting and potentially more potent high.
There are several factors that can affect the way THC is metabolized in the liver, including the individual’s age, gender, and overall health. For example, older individuals and those with liver disease may be more likely to experience adverse effects from THC metabolism. Additionally, certain medications and other drugs can affect the way THC is metabolized, potentially altering its effects.
THC can also interact with other chemicals in the body, such as endocannabinoids and enzymes, to produce different effects. For example, when THC is combined with alcohol, it can increase the impairment of cognitive and motor skills, potentially increasing the risk of accidents and other negative outcomes.
The effects of THC can vary depending on how it is ingested and processed in the body. Smoking THC can produce a more immediate and intense high, while ingesting THC can produce a longer-lasting and potentially more potent high. It’s important to note that the use of THC can also be associated with negative effects, such as memory impairment, anxiety, and psychosis, and should be used with caution.
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